Matthew Glucksberg

  1. Global Health students work to perfect technologies that aid in kangaroo mother care

    July 14, 2011 by Sarah Moore

    Eric Liu and Graham Marcy review community healthcare center (CHC) layouts with Professor Kelso during class.

    Several students have recently returned from South Africa, where they worked testing various technologies developed for maternal and neonatal healthcare.

    As part of the Global Health program, students from various levels – undergrads as well as graduates – are working on developing appropriate technologies for new mothers and babies.  Among the most important of these technologies are instruments designed to aid in kangaroo mother care, a process whereby premature infants are placed against the mother’s chest rather than in incubators.

    “We’ve become pretty convinced that it’s the right way to do things,” said Matthew Glucksberg, professor of biomedical engineering at Northwestern’s McCormick School of Engineering. “Incubators are really pretty bad places for babies to be.”

    The alternative?

    Placing babies on the mother’s chest between the breasts ensures proper temperature regulation for the infant, since this area of the mother’s body automatically adjusts to the child’s needs.  Though an ancient and very natural practice, kangaroo mother care does have its drawbacks.

    “The problem, among others, is that this isn’t going to spread until there’s instrumentation,” Glucksberg said.  In other words, there are problems the mother cannot administer to without the aid of technology.

    Premature infants can stop breathing spontaneously, for instance.  They need phototherapy for jaundice (the blue light helps bleach out bilirubin, a natural compound that results from the breakdown of blood and can make preemies look yellow).  They need CPAP, or continuous positive airway pressure, to ensure proper breathing.

    This is where project development comes in.

    “We’ve been trying to build devices that essentially are a neonatal ICU all on the mother’s chest,” Glucksberg said.

    The idea, he explained, is to bring the incubator to the mother and child, in bits and pieces.  Since the mother’s chest is such a better place for the infant to be, administering to various needs – proper breathing, blue light, etc. – should happen without separation.

    In response to this need, students have worked on testing various products – a blanket that provides blue light, a breathing apparatus that attaches to the infant’s mouth without producing sores.

    As David Kelso explained in a recent video live from Capetown, these projects were designed by previous students and some are in the process of being seriously appraised for their viability and market-readiness.

    The program, which has been ongoing for the last six years, encompasses other technologies as well.

    “What we do really falls into three general areas,” Kelso said. These areas comprise issues of preventing transmission of HIV from mother to child, saving lives at birth and upskilling healthcare workers.

    Kangaroo mother care falls into the second category, but the other two are very important in a country rife with poverty and HIV.

    The professors and students who work on these projects hope eventually to pass the results off to people within the healthcare system there.  By making sure the devices fit within already-used methods (like breastfeeding or kangaroo mother care), Northwestern’s contributions have a much greater chance of lasting impact.

    “We end up building global capacity instead of just coming in and solving people’s problems for them,” said Michael Diamond, adjunct professor in McCormick’s biomedical engineering department.

    Diamond, who has been instrumental to the development of student-driven global health efforts at Northwestern, said he believes strongly in the program’s emphasis on self-reliance.

    “There is actually a philosophy behind all these initiatives,” he said.

  2. One drop at a time: Northwestern students tackle water sanitation in a far-flung Indian desert

    July 13, 2011 by Sarah Moore

    A few weeks ago, three Masters students left for the remote Thar Desert in Rajasthan, India.

    On the docket? Investigating the water that sources 140 villages in the salty, arid desert. As part of the Global and Ecological Health Program, a Master’s-level add-on to Northwestern’s biomedical engineering degree, the program is intended to help students learn to assess and learn from problems firsthand.

    This is a skill engineers must learn from the ground up, said Matthew Glucksberg, a professor of biomedical engineering at Northwestern’s McCormick and one of the program’s coordinators.

    “You can’t just come in from the outside and expect people to implement your great idea,” Glucksberg said, adding that this is a mistake many make when they are out in the field. “Good solutions are integrated into the way people are already doing things.”

    In other words, understanding comes before solutions.

    To gain that understanding, the students will be working with the Jai Bhagirathi Foundation (JBF), an organization that oversees these villages. As such, it is geared toward the “ecological, economic and social revival of the region,” according to its website, as well as instituting community ownership and empowering villages to take part in enacting these changes.

    One of JBF’s major tenets is developing a water management system that provides clean, fresh water to all villagers. Since rains in the Thar Desert produce only 20-50 centimeters per year, “sweet” water (as opposed to saline) is a precious resource, and often hard to come by.

    As this is Northwestern’s preliminary foray into the Rajasthan region, the trip is largely exploratory: what are the problems villagers are currently facing? What secondary problems follow? Which solutions have been tried, and which have not? Perhaps most importantly, what are the primary health concerns?

    Diarrhea is a big one.

    “A lot of the population doesn’t even know that diarrhea is a problem because they’ve never known anything else,” said Glucksberg. Yet it can be fatal.

    Plus, the poverty there is unimaginable, said Kimberly Gray, a McCormick professor of civil and environmental engineering who shares oversight duties with Glucskberg.

    The list goes on: water salinity, infectious diseases, bacteria, and fecal runoff from animals and humans.

    And all of these problems have been exacerbated by recent population changes.

    “These families have lived there for literally hundreds of years and have worked out a very fragile but sustainable relationship with the environment,” said Michael Diamond, an adjunct professor in Northwestern’s biomedical engineering department and president of World Resources Chicago.

    Recent government intervention, however, has meant a significant reduction in infant mortality ate. This in turn has meant an exploding population, which the water table is having trouble coping with.

    “Our students are starting to do the assessments,” Glucksberg said. “They’re going out to the villages, going to take the samples and do a catalogue to see what the extent of the problem is at this snapshot in time.”

    Hopefully these assessments will, over time, provide opportunities to offer solutions. But that is not the main goal, Gray cautions.

    “This isn’t just us helping them,” she said. “It’s them helping us in our educational mission.”

    Glucksberg concurred, adding that the real goal of the program is student learning. “How do you make your idea stick, and not just leave a bunch of junk in a box?” he said.

    Nonetheless, both professors have high hopes for the program.

    “My greatest hope is to really develop a long-lasting partnership with JBF such that we can really develop a collaborative learning exchange program,” Gray concluded.

    The students in Rajasthan are currently unreachable due to their remote location, but they will return later this summer. Please check back for an update on their progress and an inside look at some of their successes and challenges.