Infectious Diseases

  1. Feinberg student finds new experiences in Guatemala

    March 11, 2013 by Lyz Hoffman
    Nicole Araneta counts out medications in the Pop Wuj pharmacy.Courtesy of Nicole Araneta

    Nicole Araneta counts out medications in the Pop Wuj pharmacy.Courtesy of Nicole Araneta

    Since August of last year, Feinberg student Nicole Araneta has been working in a medical clinic in Guatemala, honing her Spanish and immersing herself in a community in need of medical care. Asociación Pop Wuj, the non-profit cooperative where Araneta spends her days, offers the services of a primary care clinic for free to families involved in their community projects. Clinic services are available at a low cost to everyone else.

    When the Global Health Portal recently spoke with Araneta, she was just finishing up her time at Pop Wuj, before going on to spend her final few months in Guatemala volunteering with a hospital in another city. She said that Feinberg has been “very supportive” of her work, and that the experience has cemented her desire to be a primary care physician. She will be entering her fourth year of medical school later this year.

    Q: What made you want to study medicine abroad? How did you decide on Pop Wuj?
    A: Progressing through medical school, it became apparent to me that I want to be family medicine doctor for the underserved. This meant that making my Spanish better was a necessity as well as an aspiration. I also wanted to see medical care in an underserved setting for an extended period of time. The Global Health Office assisted me and provided a list of programs that Northwestern students had attended in the past and spoke well of. Asociación Pop Wuj, a non-profit Spanish School with community outreach projects including a primary care clinic, was on the list.

    Q: Tell me a little bit about Pop Wuj.
    A: Pop Wuj uses a holistic model in its outreach. It’s an organization that’s trying to make a difference with the communities it works with in various ways. They have a before-and-after school program, provide scholarships, build stoves for families to replace cooking over open fires, and have on-site and mobile clinics.

    One of our chronic patients is “Manuel,” a two year old with a seizure disorder. We were helping pay for specialist appointments and providing his medication. Several months ago he got sick with pneumonia when our clinic was closed. One of our health workers took him to another outreach clinic. The pediatrician there prescribed an antibiotic regimen. She also diagnosed him with chronic malnutrition, which our organization had missed. We are now working the whole family comprehensively – they will receive nutrition supplements, counseling, scholarships for the older children, a new stove, and of course continued health support for Manuel.

    Q: How is Guatemala?
    A: My experience here has been exceptional. The people are welcoming, friendly, and patient with me. I’ve seen and learned a lot. Pop Wuj has ties with several communities, so I’ve been able to do home visits where I see how different people live. Something that I didn’t know about Guatemala before coming here is how varied it is. For example – with respect to only the climate – this one small country spans mountains, coast, and tropical jungle. Through this variety of landscape and terrain have evolved many different ways of living.

    Q: Do people view medicine differently in Guatemala than people do in the U.S.?
    A: People’s ideas of illness and cure are different. There is a long history of traditional Mayan medicine that has been at odds with the western medicine in which I’ve been trained. Many Guatemalans will go to a traditional curandero before a western-trained physician (Guatemalan or foreign). If they finally get to a physician, their ailment may have advanced and the physician may scold them for “waiting it out”. But in their minds the western physician is the last resort. Only recently have the two systems started to learn to work together and respect one another – I was told that, if a patient refuses western medical care, I shouldn’t push it and to respect their decision. I also read a text by a curandera who said she used Mayan medicine for everyday aches and ailments, but that for anything acutely dangerous she would send her patients to a western physician.

    Q: What are some other common health problems that your patients experience?
    A: Most of the common diseases here are not medically complicated. They are malnutrition, diarrheal issues, and a variety of infections. In some populations there is also a notable amount of diabetes and high blood pressure, where junk/fast food and a sedentary lifestyle are becoming more common.

    What is complicated is the social context of these diseases. Malnutrition is common because of poverty, and perhaps because of some eating practices. Diarrheal infections are common because of poor water sanitation. In rural communities with the mobile clinic, I’ve seen many more advanced infections and growths that have gotten out of hand (one woman had a mass growing over her eye which she left for two years) because of lack of access to care. From some villages you would have to travel for hours and hours to get to an already busy health post.

    Q: What is a typical day like for you?
    A: A typical day is clinic from 8am-1pm then Spanish class from 2-6pm. I go home and spend time with my host family and do work for Pop Wuj’s other projects. I’ve also been a de facto health advocate for our chronic patients. “Isaías” was one of my most memorable patients. I helped him and his mom navigate the somewhat labyrinth health care system here, taking them to different diagnostic tests and specialist appointments.

    Q: Have there been any surprises?

    A: Something I was ignorant about before I came to Guatemala was the circumstance of languages. I thought everyone would speak Spanish. However, many Guatemalan’s don’t speak it as a first language. They have one of the existing 21 Mayan dialects as a native and primary language; Spanish is learned in school.

    This language situation has complicated effects. For example, parents typically keep their sons in school longer than daughters. So often men speak better Spanish – the language of government, achievement, and power here. Once, during a mobile clinic in a rural community, I was working with a female patient. All the translators helping us that day were male. I thought the patient’s clinic visit was almost over, but then the translator had to step out for a second. Immediately the patient started telling me about her gynecologic concerns, which she ostensibly was too shy to mention in front of the male translator. I had to scramble to find a woman in the village who could translate for me.

    Q: Besides medical knowledge, what have you gained from this experience?
    A: Good communication between patients and their physicians is extremely important. As is training physicians to be sympathetic of their patients’ beliefs and understanding of their ways of thinking. Being removed from my comfort zone – seeing the resilience people have developed to deal with massive poverty; simply being exposed to different points of view and approaches to life – has helped me well on my way to becoming a more culturally competent doctor.

    Q: Now that your experience with Pop Wuj is coming to a close, how do you feel?
    A: It’s sad and scary and exciting to move on to do something else. Whenever something new is on the horizon I’m nervous about it, but usually I’m glad that I did it. I will miss Pop Wuj. It’s been a good community for me. But I am excited to see how hospital medicine is practiced in Guatemala, after having spent so many months in a primary care clinic.

    To learn more about Nicole’s experiences, visit her blog at naranetacrossing.wordpress.com.

  2. From doctor to journalist, Feinberg alum discusses career in global health

    April 18, 2012 by Marguerite McNeal

    Panosian, a Feinberg alum, co-founded the global health program at UCLA, where she is a professor of medicine. She spoke about her career in global health Tuesday at Northwestern Memorial Hospital.

    What do malaria, global health and main street journalism have to do with one another? Dr. Claire Panosian Dunavan, a Feinberg alum, wove together her experience in these three fields Tuesday morning for the annual alumni lecture at Northwestern Memorial Hospital.

    Panosian had no medical expertise when she spent the summer of 1972 in Haiti. Little did she know the images of malaria, malnutrition and severe diarrhea she encountered would lead her to a career in global health.

    Panosian, currently a professor at UCLA in the infectious disease department,
    recounted stories from her experiences studying malaria in Africa and Asia. She also talked about her accidental role as a medical journalist and how it enables her to spread awareness about global health.

    In 1993, Panosian was invited to participate in a major malaria policy report that recommended subsidizing artemisinin drug combination treatments for the entire global market.

    “To see how the policy played out, both perfectly and imperfectly, has shaped my education,” she said. Subsidies for these drugs remain crucial for malaria control today.

    Experts underestimated mortality from malaria, according to a February report from The Lancet. “The study shows that mortality from malaria is about twice what we thought it was,” Panosian said. “It’s very worrisome.”

    During Panosian’s work with control policies, she noticed a surge of interest in the field of global health from young doctors. She co-founded the global health department at UCLA, where she teaches an introductory course every year.

    “I expect my students to understand health and finance indicators, such as life expectancy and fertility rates,” Panosian said. “We should all understand these statistics as global citizens.”

    The public, inundated with blogs, single-source articles and short health clips on the nightly news, is uncertain about what’s happening in medicine. “There’s a traditional role of medical experts to assist and advise professional journalists,” Panosian said.

    She encouraged fellow medical professionals to harness their expertise and use their voice to help the public understand health issues. “It isn’t as hard as you think to write an op-ed for your local paper.”

    Panosian writes about global health and other medical issues for Los Angeles Times, Scientific American and Discover Magazine. “Starting with a local audience is a great way to expand and to introduce global health,” she told the crowd of doctors and medical students. “People will turn to trustworthy sources and you are those sources for certain topics.”

  3. NU-AID establishes new site in Oaxaca

    December 7, 2011 by Bethany Hubbard

    The Oaxaca team at a weekly lecture on global health issues wearing their new brigade-vests for the upcoming fieldwork. (Muthiah Vaduganathan - bottom row, first from left, Mania Kupershtok - bottom row, first from right)

    For more than 10 years, the Northwestern University Alliance for International Development (NU-AID) has been sending medical students to Latin America to provide care for underserved populations. This past summer, for the first time, 10 students traveled to Oaxaca, Mexico to establish a new project site.

    “Prior to this trip we were going twice a year to Nicaragua,” said NU-AID board member and second year medical student Pedro Engel Gonzalez.

    Gonzalez, who helped plan the Oaxaca trip, said the site was chosen after they were given the challenge of finding a location where students could not only stay longer, but also work within the country’s medical system.

    “We decided that the Oaxaca trip provided a similar opportunity to what we were doing in Nicaragua – working with an underserved population and tropical medicine,” he said, adding that the Oaxaca trip lasted a month, significantly longer than the week-long Nicaragua trips.

    NU-AID partnered with Child Family Health International, a U.S. non-governmental organization, started many years ago by a Stanford student who wanted to provide more opportunities for medical students to work in global health in a sustainable way.

    Muthiah Vaduganathan, a fourth year medical student, was a member of the 10-person team that traveled to Oaxaca

    Public health "platica" (or lecture) attendees holding up their mosquito nets donated by the medical students.

    this past summer.

    “I was looking for a good opportunity to see real kinds of international health issues and have a global health experience,” he said. “We were able to see many clinical situations that we wouldn’t get to see in the United States.”

    The first two weeks students worked in several different clinics with local physicians. Vaduganathan said Dengue fever, a virus transmitted by mosquitos, and Chagas disease, also spread by insects, were a few of the illnesses students saw at the Oaxaca clinic.

    The second two weeks were devoted to public health issues. Vaduganathan’s team addressed the high maternal mortality rates. They spoke with midwives and 40 local women about contraceptives.

    “This is the first time they were being exposed to health workers from abroad,” he said. “We were able to integrate our talks into their existing system.”

    Mania Kupershtok, a second year medical student who was another member of the Oaxaca team, went on a previous NU-AID trip to Nicaragua. She said the Oaxaca trip was another great service-oriented opportunity.

    “They have a really strong public health foundation,” she said, citing Oaxaca’s Opportunidades program, which the NU-AID team worked in tandem with. “I was surprised at how well they are currently doing. In the poorest areas everyone was still very educated about diabetes, hypertension – even down to how it works in your body.”

    Though there is always room for more education, Vaduganathan said the people of Oaxaca are doing well with what they have.

    “Although resources and money really limit a lot of the overall care, I think with the resources they have, the Mexican health care system was actually very efficient in terms of how they utilized those resources,” he said. “Their care for every day issues was excellent.”

    Gonzalez said NU-AID plans to return to Oaxaca next summer, and though he won’t be able to join the trip then, he hopes to participate in his fourth year.

    “How to reach out to underserved populations globally is a hard topic right now,” he said. “Hopefully we’re going to be sending a trip every year.”

    Learn more about NU-AID: http://groups.northwestern.edu/nuaid/

  4. Halting pandemics in their tracks: EpidemicIQ

    October 28, 2011 by Sarah Moore

    Lalith Polepeddi is working to reduce the impacts of pandemics, and hopes one day to find ways to avoid them altogether.

    Students of Global Health 301: Introduction to International Public Health had the chance Thursday morning to talk to alumnus and researcher Lalith Polepeddi about his work tracking and preventing epidemics.

    The talk, which took place in Northwestern’s Frances Searle building and was attended by about 40 students, focused on Polepeddi’s work at Global Viral Forecasting, a San Francisco non-profit whose stated purpose is develop a global system to prevent pandemics. And how are they doing that?

    With data.

    “Our goal is to detect, track and forecast all outbreaks around the world,” said Polepeddi, who majored in biological sciences and computer science. The project, named EpidemicIQ, is part of the Global Virus Forecasting Initiative’s overall mission to reduce the amount of time between an outbreak and its spread.

    “Dramatic failures in such pandemic control, such as the ongoing lack of success in HIV vaccine development twenty-five years into the pandemic, have shown that this wait-and-respond approach is not sufficient,” states the GVFI’s website.

    It is this lag – of often two weeks, Polepeddi said – that he and others in his field find agonizing. A direct result of the fact that epidemics seem always to catch people by surprise, the lag prevents immediate action and creates spending waste. Polepeddi wants to change this “reactive” state of global health to a “predictive” one.

    To do this, he and fellow researchers collect the kinds of data that can inform them about the spread of disease. Sometimes this means medical information, but sometimes this simply means mobile phone records, or information from blogs, Facebook, Twitter.

    “The majority of the world is already connected via mobile phones,” he said, explaining that mapping phone records can paint a picture of who is connected to whom, and therefore of the lines along with a pandemic is likely to spread.

    Collecting phone data, in other words, is an accurate measure of mobility. So if there were news of an outbreak in the Democratic Republic of Congo, for example, scientists and global health workers could use phone records to overlay a network and predict along which lines the disease would spread.

    “It’s a little bit creepy,” he jokes, “but if it’s anonymized we should be able to make use of it.”

    This is one way to move from away from a reactive model and toward a predictive one. Unfortunately, changing the current state of affairs is not that easy.

    For one thing, information can sometimes be hard to come by. While news outlets and the Internet are viable sources of information in many locales around the world, in many they are not. Records from doctors visits would be useful indeed, but are largely unavailable due to doctor-patient confidentiality. Language barriers can also be a problem.

    Nonetheless, said Elizabeth Barden, who teaches the class, utilizing technology to its full potential – and especially in the ever-crucial realm of public health – is more important now than ever.

    “Harnessing it efficiently and effectively is so important,” she said, adding that Polepeddi’s approach could help students find ways to make a difference that don’t start with an MD.

    “There’s such a need for this kind of work in global health and the applications are huge,” she said. “For students it reinforces the point that you don’t need to be a physician to make a big impact.”

  5. ‘Contagion’ echoes the reality of public health outbreaks

    October 24, 2011 by Patricia Hastings

    Panelists discuss public health outbreaks on-campus and worldwide during a discussion at Northwestern University.

    Anyone who sees the Hollywood thriller “Contagion” may be a little on edge. In the film an unknown pathogen moves from Hong Kong to Chicago before globetrotting in a ruthless killing spree. The medical community struggles to contain it and find a cure as the world panics, falling into chaos.

    Could an epidemic like “Contagion” really happen?

    “Not only could it happen it already has,” said Maryn McKenna, a journalist and author specializing in infectious disease and public health.

    The author of Superbug, a book about drug-resistant staph, led a discussion at Northwestern University about “Contagion” and how the government handles health outbreaks.

    She said the film parallels the spread of the Nipah virus that swept Malaysia in 1999, which spread from bats to pigs to humans. Handshaking, kissing and dice-rolling all play a role in spreading the virus documented in the film. As the Centers for Disease Control and Prevention try to get a handle on the health panic, a blogger pushes a holistic cure.

    “All of this, remarkably, is a realistic scenario,” McKenna said.

    H5N1 bird flu was predicted to be like the disease in “Contagion.” Bird flu has a mortality rate that can reach 90 to 100 percent, often within 48 hours, according to the Centers for Disease Control and Prevention.

    The autism and MMR vaccine scare caused many parents to hold off on vaccinating their kids and opt for a more holistic approach to medicine. This shift in practice led to an outbreak of measles.

    Or how about the SARS outbreak of 2003? SARS infected thousands of people around the world before the World Health Organization could contain it.

    The film paralleled many of these moments in infectious disease history. Screenwriters even threw in a couple public health jokes: They made the Minnesota Department of Health look like idiots even though they’re one of the country’s top health departments.

    To create “Contagion”, actors went to the CDC to learn about public health outbreaks. Actual scientists also vetted the science in the film.

    “The only thing that’s wrong is it’s really too positive,” McKenna said. “We’re not in as good of shape as the government says we are.”

    “Contagion” happens over a period of a few months, when in reality it takes at least nine months to get a vaccine. McKenna said the government needs additional people and technology to move forward in preventing public health outbreaks. Most flu vaccines still use 50-year-old technology.

    When the CDC gets budget cuts, the cuts trickle down to state and local health departments. If a department isn’t testing for a disease during an outbreak because they can’t afford to, then there’s no way to determine where the disease has gone.

    McKenna said new diseases emerge almost every year. Just last week researchers discovered a new Ebola-like virus, Lloviu virus, in bats from northern Spain.

    The U.S. health care system received an overall performance score of 64 out of 100 for 2010 in a report released Tuesday by the Commonwealth Fund. The failing grade, says McKenna, speaks to larger gaps in preparedness.

Page 1 of 3123